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Literature summary for 3.4.21.27 extracted from

  • Lu, Q.; Yang, L.; Manithody, C.; Wang, X.; Rezaie, A.R.
    Expression and characterization of Gly-317 variants of factor IX causing variable bleeding in hemophilia B patients (2015), Biochemistry, 54, 3814-3821 .
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00025
-
factor IX at 25°C, pH not specified in the publication Homo sapiens
0.00035
-
factor IX mutant G317R at 25°C, pH not specified in the publication Homo sapiens
0.00038
-
factor IX mutant G317E at 25°C, pH not specified in the publication Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 5 mM used in assay conditions Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor IX + H2O
-
Homo sapiens activated factor IX + ?
-
?
factor IX mutant G317E + H2O
-
Homo sapiens ?
-
?
factor IX mutant G317R + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
factor XIa
-
Homo sapiens
FXIa
-
Homo sapiens