Literature summary for 3.4.21.27 extracted from

Kravtsov, D.V.; Matafonov, A.; Tucker, E.I.; Sun, M.F.; Walsh, P.N.; Gruber, A.; Gailani, D.
Factor XI contributes to thrombin generation in the absence of factor XII (2009), Blood, 114, 452-458.

Search for more literature for 3.4.21.27

Activating Compound

Activating Compound	Comment	Organism	Structure
thrombin	activates fXI	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
recombinant human fXI is expressed in HEK-293 cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P03951	-	-

Purification (Commentary)

Purification (Comment)	Organism
affinity chromatography	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood platelet	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide + H2O	-	Homo sapiens	L-pyroglutamyl-L-prolyl-L-arginine + p-nitroaniline	-	?
Z-Gly-Gly-Arg-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	Z-Gly-Gly-Arg + 7-amino-4-methylcoumarin	-	?

Synonyms

Synonyms	Comment	Organism
factor XI	-	Homo sapiens
FXI	-	Homo sapiens

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Release 2023.1 (January 2023)