Inhibitors | Comment | Organism | Structure |
---|---|---|---|
JTP-4819 | i.e. (S)-2-[[(S)-2-(hydroxyacetyl)-1-pyrrolidinyl]carbonyl]-N(phenylmethyl)-1-pyrrolidinecarboxamide | Homo sapiens | |
KYP-2047 | i.e. 4-phenylbutanoyl-L-prolyl-2(S)cyanopyrrolidine | Homo sapiens | |
Z-Pro-prolinal | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | enzyme activity is located only in the cytoplasm during maturation and ageing | Homo sapiens | 5737 | - |
nucleus | enzyme activity is located within the nuclei of pre-neurons | Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
SH-SY5Y cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-succinyl-Gly-L-Pro-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | N-succinyl-Gly-L-Pro + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PEP | - |
Homo sapiens |
POP | - |
Homo sapiens |
PREP | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | cytoplasmic PREP activity decreases slowly and steadily from DIV 0 throughout the growth curve until reaching confluence (between DIV 10 and 15) | down |
Homo sapiens | PREP activity inside the nucleus increases 3fold at DIV 1 compared with its initial levels, PREP nuclearactivity decline dramatically until the cells reach confluence (right after DIV 10) | up |