Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21-AI cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-({4-[2-(E)-styrylphenoxy]butanoyl}-L-4-hydroxyprolyl)-thiazolidine | SUAM-14746, selective prolyl oligopeptidase inhibitor | Homo sapiens | |
benzyloxycarbonyl-thioprolyl-thioprolinal | specific inhibitor of prolyl oligopeptidase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
glutathione Sepharose column chromatography and Mono Q 5/50 GL column chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
NB-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-succinyl-glycyl-prolyl-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | N-succinyl-glycyl-prolyl + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
POP | - |
Homo sapiens |
post-proline cleaving enzyme | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | inhibition or knockdown of prolyl oligopeptidase leads to suppression of NB-1 cell growth, and the effect is accompanied by G0/G1 arrest | Homo sapiens |
physiological function | prolyl oligopeptidase participates in cell cycle progression in human NB-1 neuroblastoma cells | Homo sapiens |