Any feedback?
Literature summary for 3.4.21.26 extracted from
- Subchronic administration of rosmarinic acid, a natural prolyl oligopeptidase inhibitor, enhances cognitive performances (2010), Fitoterapia, 81, 644-8.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| rosmarinic acid | non-competitive inhibitor | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Z-Gly-Pro-4-nitroanilide + H2O | assay at pH 7.0, 30°C | Mus musculus | Z-glycyl-L-proline + 4-nitroaniline | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| POP | - |
Mus musculus |
| prolyl oligopeptidase | - |
Mus musculus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
assay at | Mus musculus |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0637 | - |
- |
Mus musculus | rosmarinic acid | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | involved in memory-related function | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
