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Literature summary for 3.4.21.22 extracted from

  • Rusconi, C.P.; Scardino, E.; Layzer, J.; Pitoc, G.A.; Ortel, T.L.; Monroe, D.; Sullenger, B.A.
    RNA aptamers as reversible antagonists of coagulation factor IXa (2002), Nature, 419, 90-94.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
aptamer RNA aptamers isolated by iterative in vitro selection technique, complete inhibition at 0.00004 mM, inhibition is reversed by specific antidotes, i.e. oligonucleotides, complementary to the aptamers Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor X + H2O Homo sapiens
-
factor Xa
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor X + H2O
-
Homo sapiens factor Xa
-
?

Synonyms

Synonyms Comment Organism
FIXa
-
Homo sapiens