Literature summary for 3.4.21.22 extracted from

Wiebe, E.M.; Stafford, A.R.; Fredenburgh, J.C.; Weitz, J.I.
Mechanism of catalysis of inhibition of factor IXa by antithrombin in the presence of heparin or pentasaccharide (2003), J. Biol. Chem., 278, 35767-35774.

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Inhibitors

Inhibitors	Comment	Organism	Structure
antithrombin	more than 1200fold increase in inhibition in the presence of heparin, 11fold increase in inhibition in the presence of fondaparinux, 7fold increase in inhibition in the presence of 2 mM CaCl2	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
factor X + H2O	Homo sapiens	-	factor Xa	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
factor X + H2O	-	Homo sapiens	factor Xa	-	?

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Release 2023.1 (January 2023)