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Literature summary for 3.4.21.21 extracted from
- Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage (2003), J. Biol. Chem., 278, 21823-21830.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EEWEVLCWTWETCER | maximal inhibition to 74%, IC50: 1.5 nM | Homo sapiens |  |
| EEWEVLCWTWETCERGEGVEEELWEWR | maximal inhibition to 99%, IC50: 230 pM | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.00000023 | - |
maximal inhibition to 99%, IC50: 230 pM | Homo sapiens | EEWEVLCWTWETCERGEGVEEELWEWR | |
| 0.0000015 | - |
maximal inhibition to 74%, IC50: 1.5 nM | Homo sapiens | EEWEVLCWTWETCER | |
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Release 2023.1 (January 2023)
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