Activating Compound | Comment | Organism | Structure |
---|---|---|---|
lactoferrin | allosteric enhancer of the proteolytic activity of the enzyme with highest enhancing capacity under acidic (pH 5.0) conditions at 0.0025-0.25 mg/ml | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-(((S)-3-methyl-1-((S)-2-(((S)-1-((4-nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxobutan-2-yl)amino)-4-oxobutanoic acid + H2O | - |
Homo sapiens | ? | - |
? | |
MARS116 + H2O | i.e. diphenyl(1-((S)-1-((4-oxo-4-((5-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)pentyl)amino)butanoyl)-L-valyl)pyrrolidine-2-carboxamido)-2-phenylethyl)phosphonate. The reaction occurs in the presence of lactoferrin only | Homo sapiens | ? | - |
? | |
MARS123 + H2O | i.e. bis(4-methoxyphenyl) (1-((S)-1-((5-((3aS,4S,6aR)-3a,6a-dimethyl-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)-L-valyl)pyrrolidine-2-carboxamido)-3-methylbutyl)phosphonate. The reaction occurs in the presence of lactoferrin only | Homo sapiens | ? | - |
? | |
MARS125 + H2O | i.e. diphenyl(1-((S)-1-((5-((3aS,4S,6aR)-3a,6adimethyl-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)-L-valyl)pyrrolidine-2-carboxamido)-2-methylpropyl)phosphonate. The reaction occurs in the presence of lactoferrin only | Homo sapiens | ? | - |
? | |
additional information | lactoferrin is not proteolytically degraded by the enzyme | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 28500, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
CatG | - |
Homo sapiens |