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Literature summary for 3.4.21.20 extracted from

  • Virca, G.D.; Metz, G.; Schnebli, H.P.
    Similarities between human and rat leukocyte elastase and cathepsin G (1984), Eur. J. Biochem., 144, 1-9.
    View publication on PubMed
Search for more literature for 3.4.21.20

General Stability

General Stability Organism
autolysis Homo sapiens
autolysis Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Eglin c
-
 Homo sapiens
Eglin c
-
 Rattus norvegicus
additional information inhibitors from soybean and lima-bean Homo sapiens
additional information inhibitors from soybean and lima-bean Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.52
-
 N-acetyl-L-phenylalanine-p-nitrophenyl ester
-
 Rattus norvegicus
1.49
-
 methoxysuccinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Storage Stability

Storage Stability Organism
-20°C, lyophilized Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methoxy succinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
methoxy succinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide + H2O
-
 Rattus norvegicus ?
-
 ?
N-acetyl-L-Phe-p-nitrophenyl ester + H2O
-
 Homo sapiens ?
-
 ?
N-acetyl-L-Phe-p-nitrophenyl ester + H2O
-
 Rattus norvegicus ?
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
6
-
 methoxysuccinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide
-
 Homo sapiens
16.5
-
 methoxysuccinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitrophenylanilide
-
 Rattus norvegicus
20.2
-
 N-acetyl-L-phenylalanine-p-nitrophenyl ester
-
 Rattus norvegicus
68.3
-
 N-acetyl-L-phenylalanine-p-nitrophenyl ester
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
-
 Homo sapiens
8.4
-
-
 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
5.8 8 more than 50% of maximal activity at pH 5.8 and pH 8.0 Homo sapiens
6.6 8.4 pH 6.6: more than 50% of maximal activity, pH 8.4: optimum Rattus norvegicus