Literature summary for 3.4.21.120 extracted from

Lindsay, L.L.; Wieduwilt, M.J.; Hedrick, J.L.
Oviductin, the Xenopus laevis oviductal protease that processes egg envelope glycoprotein gp43, increases sperm binding to envelopes, and is translated as part of an unusual mosaic protein composed of two protease and several CUB domains (1999), Biol. Reprod., 60, 989-995.

Search for more literature for 3.4.21.120

Cloned(Commentary)

Cloned (Comment)	Organism
-	Xenopus laevis

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
gp43 + H2O	Xenopus laevis	oviductin alone is the oviductal factor responsible for converting the egg envelope to a sperm-penetrable form, via an increase in sperm binding. gp43 processing is the only requirement for envelope conversion	gp41 + ?	-	?

Organism

Organism	UniProt	Comment	Textmining
Xenopus laevis	P79953	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	protease is translated as the N terminus of an unusual mosaic protein. It is proposed that during post-translational proteolytic processing of the mosaic oviductin glycoprotein, the processed N-terminal protease domain is released coupled to two C-terminal CUB domains and constitutes the enzymatically active protease molecule	Xenopus laevis

Source Tissue

Source Tissue	Comment	Organism	Textmining
pars recta	-	Xenopus laevis	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
gp43 + H2O	oviductin alone is the oviductal factor responsible for converting the egg envelope to a sperm-penetrable form, via an increase in sperm binding. gp43 processing is the only requirement for envelope conversion	Xenopus laevis	gp41 + ?	-	?

Synonyms

Synonyms	Comment	Organism
oviductal protease	-	Xenopus laevis

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Release 2023.1 (January 2023)