Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
8-10 weeks old male ICR mice | - |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin | preference for Xaa-Arg-Arg- motif | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
submandibular gland | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0011 | - |
purified enzyme, substrate benzyloxycarbonyl-Gln-Arg-Arg-4-methyl-coumaryl-7-amide | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Arg-Val-Arg-Arg-4-methyl-coumaryl-7-amide + H2O | low activity | Mus musculus | benzyloxycarbonyl-Arg-Val-Arg-Arg + 7-amino-4-methylcoumarin | - |
? | |
benzyloxycarbonyl-Gln-Arg-Arg-4-methyl-coumaryl-7-amide + H2O | best substrate | Mus musculus | benzyloxycarbonyl-Gln-Arg-Arg + 7-amino-4-methylcoumarin | - |
? | |
benzyloxycarbonyl-Glu-Lys-Lys-4-methyl-coumaryl-7-amide + H2O | low activity | Mus musculus | benzyloxycarbonyl-Glu-Lys-Lys + 7-amino-4-methylcoumarin | - |
? | |
benzyloxycarbonyl-Leu-Lys-Arg-4-methyl-coumaryl-7-amide + H2O | - |
Mus musculus | benzyloxycarbonyl-Leu-Lys-Arg + 7-amino-4-methylcoumarin | - |
? | |
Prorenin + H2O | cleavage site at paired basic amino acid residues | Mus musculus | Renin + ? | - |
? | |
Prorenin + H2O | recombinant murine prorenin 2 | Mus musculus | Renin + ? | - |
? | |
pyroglutamyl-Arg-Tyr-Lys-Arg-4-methyl-coumaryl-7-amide + H2O | - |
Mus musculus | pyroglutamyl-Arg-Tyr-Lys-Arg + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
prorenin-converting enzyme | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Mus musculus |