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Literature summary for 3.4.21.118 extracted from

  • Tamura, H.; Ishikawa, Y.; Hino, N.; Maeda, M.; Yoshida, S.; Kaku, S.; Shiosaka, S.
    Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo (2006), J. Physiol., 570, 541-551.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information enzyme knock-out mice are significantly impaired in the Morris water maze and Y-mazes and fail to exhibit early phase long-term potentiation by a single tetanus. A dose of recombinant enzyme alone, without tetanic stimulation, elicits either long-lasting potentiation or depression, depending on the dose, by increase of phosphorylation at different sites on the GluR1 subunit of the AMPA receptor Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus enzyme is necessary for establishment of long-term potentiation and has a significant role in memory acquisition ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
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Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is necessary for establishment of long-term potentiation and has a significant role in memory acquisition Mus musculus ?
-
?