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Literature summary for 3.4.21.118 extracted from

  • Underwood, L.J.; Tanimoto, H.; Wang, Y.; Shigemasa, K.; Parmley, T.H.; O'Brien, T.J.
    Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma (1999), Cancer Res., 59, 4435-4439.
    View publication on PubMed
Search for more literature for 3.4.21.118

Application

Application Comment Organism
medicine TAGD14 may be a useful molecular target for therapy or a diagnostic tool as tumor marker due to its overexpression in ovarian carcinoma Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
DNA sequence determination and analysis Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 x * 30000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O60259 TADG14
-

Reaction

Reaction Comment Organism Reaction ID
cleavage of amide substrates following the basic amino acids Arg or Lys at the P1 position, with a preference for Arg over Lys enzyme is a trypsin-type serine protease Homo sapiens
a

Source Tissue

Source Tissue Comment Organism Textmining
ovarian carcinoma cell enzyme is overexpressed by 40-100%, overview Homo sapiens
-
ovarian carcinoma cell serous, mucinous, endometrioid, and clear cell Homo sapiens
-
ovary
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polypeptide + H2O
-
 Homo sapiens peptides
-
 ?

Subunits

Subunits Comment Organism
? x * 30000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
TADG14 i.e. tumor-associated differentially expressed gene-14 Homo sapiens