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Literature summary for 3.4.21.117 extracted from

  • Ramani, V.C.; Kaushal, G.P.; Haun, R.S.
    Proteolytic action of kallikrein-related peptidase 7 produces unique active matrix metalloproteinase-9 lacking the C-terminal hemopexin domains (2011), Biochim. Biophys. Acta, 1813, 1525-1531.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.117

Activating Compound

Activating Compound Comment Organism Structure
plasmin
-
 Homo sapiens
Thermolysin
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pro-matrix metalloproteinase-2 + H2O KLK7 degrades, but does not activate, pro-matrix metalloproteinase-2 Homo sapiens ?
-
 ?
pro-matrix metalloproteinase-9 + H2O KLK7 degrades and activates pro-matrix metalloproteinase-9, cleavage occurs between Tyr443 and Gly444 Homo sapiens matrix metalloproteinase-9 the product is a truncated, active matrix metalloproteinase-9 lacking the C-terminal hemopexin domains which is not generated by other proteases ?

Synonyms

Synonyms Comment Organism
kallikrein-related peptidase 7
-
 Homo sapiens
KLK7
-
 Homo sapiens