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Literature summary for 3.4.21.112 extracted from
- YpdC determines site-1 degradation in regulated intramembrane proteolysis of the RsiW anti-sigma factor of Bacillus subtilis (2006), Mol. Microbiol., 62, 566-579.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Bacillus subtilis |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | in a ypdC null mutant, induction of sigmaW-controlled genes is abolished and site-1 proteolysis of RsiW is completely blocked. Defect of sigmaW induction is complemented by ectopically integrated ypdC under xylose control in a heterologous Escherichia coli system | Bacillus subtilis |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | YpdC contains five transmembrane segments and two larger extracytoplasmic loops | Bacillus subtilis | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RsiW + H2O | site-1 proteolysis of RsiW. Is converted to a C-terminally truncated form that remains membrane bound | Bacillus subtilis | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| protease responsible for activating sigmaW | - |
Bacillus subtilis |
| PrsW | - |
Bacillus subtilis |
| YPDC | - |
Bacillus subtilis |
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