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Literature summary for 3.4.21.110 extracted from

  • Wexler, D.E.; Chenoweth, D.E.; Cleary, P.P.
    Mechanism of action of the group A streptococcal C5a inactivator (1985), Proc. Natl. Acad. Sci. USA, 82, 8144-8148.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information greatly reduces ability to bind to receptors of polymorphonuclear leukocytes as compared with native C5a, inactivation is temperature dependent, mediates a small decrease in the molecular weight of C5adesArg and a six-residue peptide in inactivated C5a is lost Streptococcus sp.

Organism

Organism UniProt Comment Textmining
Streptococcus sp.
-
M49T14 group A streptococci
-

Purification (Commentary)

Purification (Comment) Organism
standard method Streptococcus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chemotaxin C5a + H2O
-
Streptococcus sp. ?
-
?
additional information native bovine serum albumin and other native proteins are highly resistant to proteolysis Streptococcus sp. ?
-
?

Synonyms

Synonyms Comment Organism
SCFI
-
Streptococcus sp.
streptococcal chemotactic factor inactivator
-
Streptococcus sp.