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Literature summary for 3.4.21.110 extracted from

  • Terao, Y.; Yamaguchi, M.; Hamada, S.; Kawabata, S.
    Multifunctional glyceraldehyde-3-phosphate dehydrogenase of Streptococcus pyogenes is essential for evasion from neutrophils (2006), J. Biol. Chem., 281, 14215-14223.
    View publication on PubMed
Search for more literature for 3.4.21.110

Application

Application Comment Organism
additional information ScpA and the multifunctional protein streptococcal plasmin receptor/surface dehydrogenase/glyceraldehyde-3-phosphate dehydrogenase are both necessary for the cleavage of C5a on the bacterial surface Streptococcus pyogenes

Protein Variants

Protein Variants Comment Organism
additional information isogenic scpA-deficient mutant strain TR-9 Streptococcus pyogenes

Inhibitors

Inhibitors Comment Organism Structure
anti-ScpA antibody
-
 Streptococcus pyogenes

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
-
-
Streptococcus pyogenes SSI-9
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Streptococcus pyogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chemotaxin C5a + H2O
-
 Streptococcus pyogenes ?
-
 ?
chemotaxin C5a + H2O
-
 Streptococcus pyogenes SSI-9 ?
-
 ?
additional information no cleavage of rGST-enhanced green fluorescent protein Streptococcus pyogenes ?
-
 ?
additional information no cleavage of rGST-enhanced green fluorescent protein Streptococcus pyogenes SSI-9 ?
-
 ?
rGST-C5a-enhanced green fluorescent protein + H2O
-
 Streptococcus pyogenes ?
-
 ?
rGST-C5a-enhanced green fluorescent protein + H2O
-
 Streptococcus pyogenes SSI-9 ?
-
 ?

Synonyms

Synonyms Comment Organism
SCPA
-
 Streptococcus pyogenes