Literature summary for 3.4.21.108 extracted from

Luo, F.; Wei, L.; Sun, C.; Chen, X.; Wang, T.; Li, Y.; Liu, Z.; Chen, Z.; Xu, P.
HtrA2/Omi is involved in 6-OHDA-induced endoplasmic reticulum stress in SH-SY5Y cells (2012), J. Mol. Neurosci., 47, 120-127.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O43464	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
SH-SY5Y cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
HtrA2/Omi	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	the expression level of HtrA2/Omi decreases with endoplasmic reticulum stress induction in 6-hydroxydopamine-treated SH-SY5Y cells	down

General Information

General Information	Comment	Organism
physiological function	silencing endogenous expression of HtrA2/Omi with siRNA results in aggregated endoplasmic reticulum stress and cell death. The expression level of HtrA2/Omi decreases with endoplasmic reticulum stress induction in 6-hydroxydopamine-treated SH-SY5Y cells	Homo sapiens

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Release 2023.1 (January 2023)