Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | Omi/HtrA2 is principally localized to the cytoplasm | Homo sapiens | 5737 | - |
mitochondrion | S-nitrosoglutathione treatment induces redistribution of Omi/HtrA2 from cytoplasm to mitochondria in endothelial cells | Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
EAhy 926 cell | - |
Homo sapiens | - |
endothelial cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
Omi/HtrA2 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | S-nitrosoglutathione treatment significantly decreases mitochondrial Omi/HtrA2 content after 8 h of exposure in endothelial cells | down |
Homo sapiens | S-nitrosoglutathione treatment significantly increases cytosolic Omi/HtrA2 content after 8 h of exposure in endothelial cells | up |
General Information | Comment | Organism |
---|---|---|
malfunction | loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells | Homo sapiens |