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Literature summary for 3.4.21.108 extracted from
- Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer (2008), Clin. Biochem., 41, 561-569.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | released into the cytosol upon apoptotic stimuli | Homo sapiens | 5829 | - |
| mitochondrion | released into the cytosol upon apoptotic stimuli | Homo sapiens | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 40000 | - |
determined by SDS-PAGE and Western Blot analysis | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | degradation of inhibitor of apoptosis proteins, IAPs | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ovary | - |
Homo sapiens | - |
| ovary cancer cell | benign tumor, borderline tumor, cancer, Krukenberg tumor | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | degradation of inhibitor of apoptosis proteins, IAPs | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HtrA2 | - |
Homo sapiens |
| Omi | - |
Homo sapiens |
| serine protease | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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