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Literature summary for 3.4.21.108 extracted from

  • Tain, L.S.; Chowdhury, R.B.; Tao, R.N.; Plun-Favreau, H.; Moisoi, N.; Martins, L.M.; Downward, J.; Whitworth, A.J.; Tapon, N.
    Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin (2009), Cell Death Differ., 16, 1118-1125.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.108

Application

Application Comment Organism
medicine HtrA2 is linked to Parkinsons disease Drosophila melanogaster

Cloned(Commentary)

Cloned (Comment) Organism
into the vectors pCaSpeR-HS and pUASp Drosophila melanogaster

Protein Variants

Protein Variants Comment Organism
HtrA2DELTA1 deletion mutant, the P-element G4907 is excised to produce a deletion of 1037 bp Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Drosophila melanogaster 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 cleaved form, mitochondrial import Drosophila melanogaster
37000
-
 cleaved form, mitochondrial import Drosophila melanogaster
46000
-
 full-length protein Drosophila melanogaster

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster Q9VFJ3
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
 Drosophila melanogaster

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Drosophila melanogaster
-
neuron
-
 Drosophila melanogaster
-
testis
-
 Drosophila melanogaster
-
thorax
-
 Drosophila melanogaster
-

Synonyms

Synonyms Comment Organism
high temperature requirement A2
-
 Drosophila melanogaster
HtrA2
-
 Drosophila melanogaster
HtrA2/Omi
-
 Drosophila melanogaster