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Literature summary for 3.4.21.107 extracted from

  • Hauske, P.; Meltzer, M.; Ottmann, C.; Krojer, T.; Clausen, T.; Ehrmann, M.; Kaiser, M.
    Selectivity profiling of DegP substrates and inhibitors (2009), Bioorg. Med. Chem., 17, 2920-2924.
    View publication on PubMed
Search for more literature for 3.4.21.107

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by SGRVVPGYGHA-chloromethylketone and IWNTLNSGRVVPGTGHA-chloromethylketone Escherichia coli
PMMGKASPV-chloromethylketone 49% residual activity at 0.5 mM Escherichia coli
PVFNTLPMMGKASPV-chloromethylketone 63% residual activity at 0.5 mM Escherichia coli
SPMFKGV-chloromethylketone 3% residual activity at 0.5 mM Escherichia coli
VFNTLPMMGKASPV-chloromethylketone 57% residual activity at 0.5 mM Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.001
-
 using PMMGKASPV-4-nitroanilide as substrate, in 50 mM NaH2PO4, pH 8.0, temperature not specified in the publication Escherichia coli
0.018
-
 using PVFNTLPMMGKASPV-4-nitroanilide as substrate, in 50 mM NaH2PO4, pH 8.0, temperature not specified in the publication Escherichia coli
0.018
-
 using SPMFKGV-4-nitroanilide as substrate, in 50 mM NaH2PO4, pH 8.0, temperature not specified in the publication Escherichia coli
0.032
-
 using VFNTLPMMGKASPV-4-nitroanilide as substrate, in 50 mM NaH2PO4, pH 8.0, temperature not specified in the publication Escherichia coli
0.473
-
 using DPMFKLV-4-nitroanilide as substrate, in 50 mM NaH2PO4, pH 8.0, temperature not specified in the publication Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DPMFKLV-4-nitroanilide + H2O
-
 Escherichia coli DPMFKLV + 4-nitroaniline
-
 ?
additional information almost no activity towards SDAEFRHDSGYEV-4-nitroanilide, SDAEFRHDSGYEV-4-nitroanilide, SGRVVPGYGHA-4-nitroanilide, SPLPEGV-4-nitroanilide , GLATGNVSTAELQDATPA-4-nitroanilide, KGKNSGSGATPV-4-nitroanilide, KGASVPGAGLV-4-nitroanilide, SPAKGGEEPLPEGV-4-nitroanilide, and benzoyl-L-Arg-4-nitroanilide Escherichia coli ?
-
 ?
PMMGKASPV-4-nitroanilide + H2O
-
 Escherichia coli PMMGKASPV + 4-nitroaniline
-
 ?
PVFNTLPMMGKASPV-4-nitroanilide + H2O
-
 Escherichia coli PVFNTLPMMGKASPV + 4-nitroaniline
-
 ?
SPMFKGV-4-nitroanilide + H2O
-
 Escherichia coli SPMFKGV + 4-nitroaniline
-
 ?
VFNTLPMMGKASPV-4-nitroanilide + H2O
-
 Escherichia coli VFNTLPMMGKASPV + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
DegP
-
 Escherichia coli