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Literature summary for 3.4.21.107 extracted from

  • Skorko-Glonek, J.; Lipinska, B.; Krzewski, K.; Zolese, G.; Bertoli, E.; Tanfani, F.
    HtrA heat shock protease interacts with phospholipid membranes and undergoes conformational changes (1997), J. Biol. Chem., 272, 8974-8982.
    View publication on PubMed
Search for more literature for 3.4.21.107

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylglycerol activates at 37-45°C Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
cardiolipin
-
 Escherichia coli
phosphatidylglycerol inhibits activity at 50-55°C Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at temperatures above 42°C ?
-
 ?
Protein + H2O Escherichia coli
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-casein + H2O
-
 Escherichia coli ?
-
 ?
additional information involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at temperatures above 42°C Escherichia coli ?
-
 ?
Protein + H2O
-
 Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
HtrA
-
 Escherichia coli

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
additional information
-
 interaction with phosphatidylgycerol leads to a remarkable decrease in the thermal stability Escherichia coli