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Literature summary for 3.4.21.107 extracted from

  • Skorko-Glonek, J.; Krzewski, K.; Lipinska, B.; Bertoli, E.; Tanfani, F.
    Comparison of the structure of wild-type HtrA heat shock protease and mutant HtrA proteins. A Fourier transform infrared spectroscopic study (1995), J. Biol. Chem., 270, 11140-11146.
    View publication on PubMed
Search for more literature for 3.4.21.107

Protein Variants

Protein Variants Comment Organism
H105R loss of protease activity, no change in secondary structure Escherichia coli
S210A loss of protease activity, no change in secondary structure Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
diisopropyl fluorophosphates
-
 Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
inner membrane periplasmatic side of the membrane Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at temperatures above 42°C ?
-
 ?
Protein + H2O Escherichia coli
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-casein + H2O
-
 Escherichia coli ?
-
 ?
additional information involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at temperatures above 42°C Escherichia coli ?
-
 ?
Protein + H2O
-
 Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
HtrA heat shock protease
-
 Escherichia coli

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
55
-
-
 Escherichia coli

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
37 55 activity rapidly increases with temperature Escherichia coli

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
45
-
 stable for at least 4 h Escherichia coli
50
-
 stable for at least 1.5 h Escherichia coli
55
-
 stable for at least 1 h Escherichia coli
55 75 denaturation of the enzyme starts at 55°C and ends at 75°C Escherichia coli
60
-
 drastic decrease of activity within 5 min Escherichia coli