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Literature summary for 3.4.21.105 extracted from
- Distinct roles of Plasmodium Rhomboid 1 in parasite development and malaria pathogenesis (2009), PLoS Pathog., 5, e1000262.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| apical part of cell | in blood stage merozoites, PbROM1 localizes to the apical end where proteins involved in invasion are also present | Plasmodium berghei | 45177 | - |
| cell surface | PbROM1 localizes to the surface of sporozoites after salivary gland invasion | Plasmodium berghei | 9986 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Plasmodium berghei | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PbROM1 | - |
Plasmodium berghei |
| rhomboid protease | - |
Plasmodium berghei |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | whereas wild-type Plasmodium berghei is lethal to mice, animals infected with PbROM1 null mutants clear the parasites efficiently and develop long-lasting protective immunity | Plasmodium berghei |
| physiological function | PbROM1 functions in the invasive stages of parasite development | Plasmodium berghei |
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Release 2023.1 (January 2023)
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