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Literature summary for 3.4.21.105 extracted from
- Mononeme: a new secretory organelle in Plasmodium falciparum merozoites identified by localization of rhomboid-1 protease (2007), Proc. Natl. Acad. Sci. USA, 104, 20043-20048.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mononeme | merozoite apical pole and the posterior pole, a single thread-like organelle in merozoites, immunohistochemic detection, overview | Plasmodium falciparum | 70074 | - |
| additional information | release of merozoites from infected erythrocytes triggers the movement of ROM1 to the merozoite surface, overview | Plasmodium falciparum | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Plasmodium falciparum | a protease that cleaves the transmembrane regions of proteins involved in parasite invasion | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Plasmodium falciparum | A8IWX2 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| merozoite | ROM1 is localized to a single, thread-like structure on one side of the merozoites that appears to be in close proximity to the subpellicular microtubules, ROM1 is not associated with micronemes, rhoptries, or dense granules, the three identified secretory organelles of invasion, immunohistochemic detection, overview | Plasmodium falciparum | - |
| schizont | - |
Plasmodium falciparum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | a protease that cleaves the transmembrane regions of proteins involved in parasite invasion | Plasmodium falciparum | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| rhomboid-1 | - |
Plasmodium falciparum |
| rhomboid-1 protease | - |
Plasmodium falciparum |
| ROM1 | - |
Plasmodium falciparum |
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