Cloned (Comment) | Organism |
---|---|
co-expression of Rhomboid-1 with growth factor Spitz in COS-7 cells | Drosophila melanogaster |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | intramembrane enzyme with 6 transmembrane segments | Drosophila melanogaster | 16020 | - |
membrane | intramembrane enzyme with 6 transmembrane segments | Escherichia coli | 16020 | - |
membrane | intramembrane enzyme with 6 transmembrane segments | Haemophilus influenzae | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
growth factor Spitz + H2O | Drosophila melanogaster | Rhomboid-1 | ? | - |
? | |
additional information | Drosophila melanogaster | regulation, overview | ? | - |
? | |
additional information | Escherichia coli | regulation, overview | ? | - |
? | |
additional information | Haemophilus influenzae | regulation, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Escherichia coli | - |
gene glpG | - |
Haemophilus influenzae | P44783 | gene glpG | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains | rhomboid structure and catalytic mechanism, catalytic dyad id formed by S201 and H254, structure-function modeling | Escherichia coli | |
cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains | rhomboid structure and catalytic mechanism, catalytic dyad id formed by S201 and H254, structure-function modeling | Haemophilus influenzae | |
cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains | rhomboid structure and catalytic mechanism, structure-function modeling | Drosophila melanogaster |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
growth factor Spitz + H2O | Rhomboid-1 | Drosophila melanogaster | ? | - |
? | |
additional information | regulation, overview | Drosophila melanogaster | ? | - |
? | |
additional information | regulation, overview | Escherichia coli | ? | - |
? | |
additional information | regulation, overview | Haemophilus influenzae | ? | - |
? | |
additional information | structure-function relationship, substrate entry, overview | Escherichia coli | ? | - |
? | |
additional information | structure-function relationship, substrate entry, overview | Haemophilus influenzae | ? | - |
? | |
additional information | structure-function relationship, substrate entry, Rhomboid active-site topology, overview | Drosophila melanogaster | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | molecular structure, alternative conformations for the putative gating helix 5 of GlpG, GlpG forms a water-filled cavity on the extracellular side of GlpG, with the catalytic serine at its base, overview | Escherichia coli |
More | molecular structure, alternative conformations for the putative gating helix 5 of GlpG, overview | Haemophilus influenzae |
Synonyms | Comment | Organism |
---|---|---|
GlpG | - |
Escherichia coli |
GlpG | - |
Haemophilus influenzae |
rhomboid-1 | - |
Drosophila melanogaster |