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Literature summary for 3.4.21.104 extracted from

  • Cseh, S.; Vera, L.; Matsushita, M.; Fujita, T.; Arlaud, G.J.; Thielens, N.M.
    Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2 (2002), J. Immunol., 169, 5735-5743.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
1 * 45000 + 1 * 28000, SDS-PAGE, reducing conditions Homo sapiens
45000
-
1 * 45000 + 1 * 28000, SDS-PAGE, reducing conditions Homo sapiens
80000
-
SDS-PAGE, non-reducing conditions Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens L-ficolin/P35 competes with mannose-binding protein for Ca2+-dependent binding to MASP-2, complex activates complement ?
-
?
Protein + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information L-ficolin/P35 competes with mannose-binding protein for Ca2+-dependent binding to MASP-2, complex activates complement Homo sapiens ?
-
?
Protein + H2O
-
Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
dimer 1 * 45000 + 1 * 28000, SDS-PAGE, reducing conditions Homo sapiens

Synonyms

Synonyms Comment Organism
MASP-2
-
Homo sapiens