Literature summary for 3.4.21.10 extracted from

Zhang, G.; Yang, W.; Zou, P.; Jiang, F.; Zeng, Y.; Chen, Q.; Sun, L.; Yang, H.; Zhou, N.; Wang, X.; Liu, J.; Cao, J.; Zhou, Z.; Ao, L.
Mitochondrial functionality modifies human sperm acrosin activity, acrosome reaction capability and chromatin integrity (2019), Hum. Reprod., 34, 3-11 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
semen	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Nalpha-benzoyl-DL-arginine-4-nitroanilide + H2O	-	Homo sapiens	Nalpha-benzoyl-DL-arginine + 4-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
sperm acrosin	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	mitochondrial membrane potential dissipation induced by 0.01 mM carbonyl cyanide 3-chlorophenylhydrazone causes significant declines in acrosin activity	down
Homo sapiens	there is significantly higher acrosin activity in subjects with moderate or high mitochondrial membrane potential compared to those with low mitochondrial membrane potential	up

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Release 2023.1 (January 2023)