Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NaF | - |
Homo sapiens | |
p-Aminobenzoate | 0.1 mM: no inhibition, 30% inhibition at 1.0 mM | Homo sapiens | |
substituted and reduced pteroylglutamate | 0.1 mM: not, 30% inhibition at 1.0 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00055 | - |
Pteroyltriglutamate | - |
Homo sapiens | |
0.0006 | - |
Pteroylheptaglutamate | - |
Homo sapiens | |
0.0006 | - |
pteroyldiglutamate | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | slight activation | Homo sapiens | |
Ca2+ | activation | Homo sapiens | |
Cd2+ | slight activation | Homo sapiens | |
Fe2+ | slight activation | Homo sapiens | |
Mg2+ | slight activation | Homo sapiens | |
Mg2+ | activation | Homo sapiens | |
Mn2+ | slight activation | Homo sapiens | |
Mn2+ | activation | Homo sapiens | |
Ni2+ | slight activation | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
115000 | - |
x * 145000 + x * 115000, SDS/urea PAGE | Homo sapiens |
145000 | - |
x * 145000 + x * 115000, SDS/urea PAGE | Homo sapiens |
700000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
jejunum | mucosal brush-border | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pteroyldiglutamate + H2O | - |
Homo sapiens | ? | - |
? | |
pteroylheptaglutamate + H2O | - |
Homo sapiens | ? | - |
? | |
pteroyltriglutamate + H2O | - |
Homo sapiens | ? | - |
? | |
pteroyltriglutamate + H2O | - |
Homo sapiens | pteroylglutamate + glutamate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 145000 + x * 115000, SDS/urea PAGE | Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
- |
Homo sapiens |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
about 25% of activity maximum at 30°C and 80°C | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
65 | - |
up to, for at least 90 min | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
4 | 7 | about 45% of activity maximum at pH 4 and pH 7 | Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
stable at pH 6.5 and above, 90 min | Homo sapiens |