BRENDA - Enzyme Database
show all sequences of 3.4.19.3

A study of a highly specific pyroglutamyl aminopeptidase type-II from the membrane fraction of bovine brain

Gallagher, S.P.; O'Connor, B.; Int. J. Biochem. Cell Biol. 30, 115-133 (1998)

Data extracted from this reference:

General Stability
General Stability
Organism
addition of 1% bovine serum albumin to the purified enzyme improves stability with 88% of the activity remaining after 4 days at 4C and 93% of the activity remaining after 21 days at -80C
Bos taurus
enzyme solubilized by sodium deoxycholate and Triton X-100, -20C or 4C, 24 h, more than 50% loss of activity
Bos taurus
trypsin solubilized enzyme, no loss of activity after 14 days at 4C, 20% loss of activity after 14 days at -20C
Bos taurus
Inhibitors
Inhibitors
Commentary
Organism
Structure
1,10-phenanthroline
-
Bos taurus
1,7-phenanthroline
-
Bos taurus
4,7-phenanthroline
-
Bos taurus
4-(2-aminoethyl)-benzenesulfonylfluoride
-
Bos taurus
8-hydroxyquinoline
-
Bos taurus
Cd2+
-
Bacillus amyloliquefaciens
Cd2+
CdSO4
Bos taurus
Dithiobisnitrobenzoate
-
Bos taurus
dithiothreitol
-
Bos taurus
EGTA
-
Bos taurus
Hg2+
-
Bacillus amyloliquefaciens
Hg2+
HgSO4
Bos taurus
luteinizing hormone releasing hormone 1-5
-
Bos taurus
thioglycolic acid
-
Bos taurus
Zn2+
ZnSO4
Bos taurus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.00253
-
pyroglutamyl-His-Pro-4-methylcoumarin 7-amide
-
Bos taurus
0.4198
-
pyroglutamyl-His-Pro-4-methylcoumarin 7-amide
-
Bos taurus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Bos taurus
16020
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
CoSO4
activates
Bos taurus
additional information
metallopeptidase
Bos taurus
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
214000
-
gel filtration
Bos taurus
Organism
Organism
UniProt
Commentary
Textmining
Bacillus amyloliquefaciens
-
-
-
Bacillus subtilis
-
-
-
Bos taurus
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Bos taurus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Bos taurus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
0.0208
-
-
Bos taurus
Storage Stability
Storage Stability
Organism
-20C or 4C, 24 h, more than 50% loss of activity of the enzyme solubilized by sodium deoxycholate and Triton X-100
Bos taurus
4C, 72 h, 10% loss of activity of the enzyme solubilized in CHAPS
Bos taurus
4C, 72 h, 60% loss of activity of the enzyme solubilized in CHAPS
Bos taurus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
L-pyroglutamyl-His-Pro-4-methylcoumarin 7-amide + H2O
-
95299
Bos taurus
L-pyroglutamate + His-Pro-4-methylcoumarin 7-amide
-
-
-
?
pyroglutamyl-4-methylcoumarin 7-amide + H2O
-
95299
Bos taurus
pyroglutamate + 7-amino-4-methylcoumarin
-
-
-
?
pyroglutamyl-His-Gly + H2O
-
95299
Bos taurus
pyroglutamate + His-Gly
-
-
-
?
pyroglutamyl-His-Gly-NH2 + H2O
-
95299
Bos taurus
pyroglutamate + His-Gly-NH2
-
-
-
?
pyroglutamyl-His-Pro-Gly + H2O
-
95299
Bos taurus
pyroglutamate + His-Pro-Gly
-
-
-
?
pyroglutamyl-His-Pro-Gly-NH2 + H2O
-
95299
Bos taurus
pyroglutamate + His-Pro-Gly-NH2
-
-
-
?
pyroglutamyl-Phe-Pro-NH2 + H2O
-
95299
Bos taurus
pyroglutamate + Phe-Pro-NH2
-
-
-
?
thyroliberin + H2O
-
95299
Bos taurus
pyroglutamate + His-Pro-NH2
-
-
-
?
Temperature Optimum [C]
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
45
-
-
Bos taurus
Temperature Stability [C]
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
45
-
stable for at least 1 h
Bos taurus
55
-
partial inactivation
Bos taurus
60
-
2 min, total inactivation
Bos taurus
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.8
7.6
-
Bos taurus
pH Range
pH Minimum
pH Maximum
Commentary
Organism
6
8.5
pH 6.5: about 45% of maximal activity, pH 8.5: about 25% of maximal activity
Bos taurus
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
4
9.2
rapid inactivation below pH 4.0 and above pH 9.2
Bos taurus
General Stability (protein specific)
General Stability
Organism
addition of 1% bovine serum albumin to the purified enzyme improves stability with 88% of the activity remaining after 4 days at 4C and 93% of the activity remaining after 21 days at -80C
Bos taurus
enzyme solubilized by sodium deoxycholate and Triton X-100, -20C or 4C, 24 h, more than 50% loss of activity
Bos taurus
trypsin solubilized enzyme, no loss of activity after 14 days at 4C, 20% loss of activity after 14 days at -20C
Bos taurus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
1,10-phenanthroline
-
Bos taurus
1,7-phenanthroline
-
Bos taurus
4,7-phenanthroline
-
Bos taurus
4-(2-aminoethyl)-benzenesulfonylfluoride
-
Bos taurus
8-hydroxyquinoline
-
Bos taurus
Cd2+
-
Bacillus amyloliquefaciens
Cd2+
CdSO4
Bos taurus
Dithiobisnitrobenzoate
-
Bos taurus
dithiothreitol
-
Bos taurus
EGTA
-
Bos taurus
Hg2+
-
Bacillus amyloliquefaciens
Hg2+
HgSO4
Bos taurus
luteinizing hormone releasing hormone 1-5
-
Bos taurus
thioglycolic acid
-
Bos taurus
Zn2+
ZnSO4
Bos taurus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.00253
-
pyroglutamyl-His-Pro-4-methylcoumarin 7-amide
-
Bos taurus
0.4198
-
pyroglutamyl-His-Pro-4-methylcoumarin 7-amide
-
Bos taurus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Bos taurus
16020
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
CoSO4
activates
Bos taurus
additional information
metallopeptidase
Bos taurus
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
214000
-
gel filtration
Bos taurus
Purification (Commentary) (protein specific)
Commentary
Organism
-
Bos taurus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Bos taurus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
0.0208
-
-
Bos taurus
Storage Stability (protein specific)
Storage Stability
Organism
-20C or 4C, 24 h, more than 50% loss of activity of the enzyme solubilized by sodium deoxycholate and Triton X-100
Bos taurus
4C, 72 h, 10% loss of activity of the enzyme solubilized in CHAPS
Bos taurus
4C, 72 h, 60% loss of activity of the enzyme solubilized in CHAPS
Bos taurus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
L-pyroglutamyl-His-Pro-4-methylcoumarin 7-amide + H2O
-
95299
Bos taurus
L-pyroglutamate + His-Pro-4-methylcoumarin 7-amide
-
-
-
?
pyroglutamyl-4-methylcoumarin 7-amide + H2O
-
95299
Bos taurus
pyroglutamate + 7-amino-4-methylcoumarin
-
-
-
?
pyroglutamyl-His-Gly + H2O
-
95299
Bos taurus
pyroglutamate + His-Gly
-
-
-
?
pyroglutamyl-His-Gly-NH2 + H2O
-
95299
Bos taurus
pyroglutamate + His-Gly-NH2
-
-
-
?
pyroglutamyl-His-Pro-Gly + H2O
-
95299
Bos taurus
pyroglutamate + His-Pro-Gly
-
-
-
?
pyroglutamyl-His-Pro-Gly-NH2 + H2O
-
95299
Bos taurus
pyroglutamate + His-Pro-Gly-NH2
-
-
-
?
pyroglutamyl-Phe-Pro-NH2 + H2O
-
95299
Bos taurus
pyroglutamate + Phe-Pro-NH2
-
-
-
?
thyroliberin + H2O
-
95299
Bos taurus
pyroglutamate + His-Pro-NH2
-
-
-
?
Temperature Optimum [C] (protein specific)
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
45
-
-
Bos taurus
Temperature Stability [C] (protein specific)
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
45
-
stable for at least 1 h
Bos taurus
55
-
partial inactivation
Bos taurus
60
-
2 min, total inactivation
Bos taurus
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.8
7.6
-
Bos taurus
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
6
8.5
pH 6.5: about 45% of maximal activity, pH 8.5: about 25% of maximal activity
Bos taurus
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
4
9.2
rapid inactivation below pH 4.0 and above pH 9.2
Bos taurus
Other publictions for EC 3.4.19.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
754260
Compton
Evaluation of pyrrolidonyl ar ...
Enterococcus faecalis, Enterococcus faecalis ATCC 29212, no activity in Staphylococcus aureus, no activity in Staphylococcus aureus ATCC 25923, no activity in Staphylococcus pseudintermedius, no activity in Staphylococcus pseudintermedius LMG 22219T, Staphylococcus delphini, Staphylococcus delphini 49-046, Staphylococcus delphini 52-006, Staphylococcus delphini 53-033, Staphylococcus delphini 56-021, Staphylococcus delphini 56-039, Staphylococcus delphini 62-031, Staphylococcus delphini MI 09-2894, Staphylococcus delphini MI 09-8445, Staphylococcus delphini MI 16-1129, Staphylococcus delphini VPP 12 D, Staphylococcus pseudintermedius, Staphylococcus pseudintermedius LMG 22219T
J. Clin. Microbiol.
55
859-864
2017
-
1
-
-
-
-
-
-
-
-
-
-
-
22
-
-
-
-
-
-
-
-
19
-
10
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
19
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
731717
Megias
Serum pyroglutamyl aminopeptid ...
Homo sapiens
Endocr. Regul.
49
20-24
2015
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
731297
Mizuguchi
Structural characterization of ...
Pyrococcus furiosus
Biochemistry
51
6089-6096
2012
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
731568
Carrera-Gonzalez
Putative relationship between ...
Homo sapiens
Breast
21
751-754
2012
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
708574
Marinho
Seasonal variation of peptidas ...
Crotalus durissus terrificus
Gen. Comp. Endocrinol.
160
84-92
2009
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
1
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
678264
Iimura
Characterization of the denatu ...
Pyrococcus furiosus
Biochemistry
46
3664-3672
2007
-
1
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
681896
Kilbane
Cloning and heterologous expre ...
Bos taurus
Mol. Cell. Biochem.
297
189-197
2007
1
-
1
-
-
-
3
1
-
-
2
-
-
4
-
-
1
-
-
-
2
-
1
1
2
1
-
-
1
1
1
-
-
3
-
-
1
-
1
-
-
-
-
-
3
3
1
-
-
2
-
-
-
-
1
-
-
2
-
1
1
1
-
-
1
1
1
-
-
-
-
-
-
-
-
682252
Zambotti-Villela
Prolyl, cystyl and pyroglutamy ...
Rattus norvegicus
Peptides
28
1586-1595
2007
2
1
-
-
-
-
5
-
2
-
-
-
-
4
-
-
-
-
-
3
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
5
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
682806
Agirregoitia
Ontogeny of prolyl endopeptida ...
Rattus norvegicus
Regul. Pept.
139
52-58
2007
1
-
-
-
-
-
-
-
2
-
-
-
-
2
-
-
-
-
-
7
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
7
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
667525
Morty
Pyroglutamyl peptidase type I ...
Trypanosoma brucei, Trypanosoma brucei brucei, Trypanosoma brucei gambiense, Trypanosoma brucei rhodesiense
Biochem. J.
394
635-645
2006
-
-
1
-
-
-
1
8
-
-
-
1
-
4
-
-
1
-
-
5
1
-
5
-
-
-
-
1
8
1
1
-
-
1
-
-
-
-
1
-
-
-
-
-
1
1
8
-
-
-
1
-
-
-
1
-
5
1
-
5
-
-
-
1
8
1
1
-
-
-
-
-
-
-
-
667733
Kaushik
Completely buried, non-ion-pai ...
Pyrococcus furiosus
Biochemistry
45
7100-7112
2006
-
-
-
1
5
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
2
-
-
-
-
-
-
-
-
1
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
2
-
-
-
-
-
-
-
668475
Monsuur
Genetic and functional analysi ...
Homo sapiens
Eur. J. Gastroenterol. Hepatol.
18
637-644
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
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1
-
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1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
678405
Hellstroem
Unfolding of the immunoglobuli ...
Pyrococcus furiosus
Biochim. Biophys. Acta
1764
1735-1740
2006
2
-
1
-
-
-
-
-
-
-
-
-
-
2
-
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1
-
-
-
-
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2
-
2
-
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-
-
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2
-
1
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1
-
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2
-
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Pyrrolidon (sic) carboxypeptid ...
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Pyroglutamyl aminopeptidase I, ...
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Marginal involvement of pyrogl ...
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Pyroglutamyl peptidase I and p ...
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Pyroglutamyl-peptidase I: clon ...
Homo sapiens
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28
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2003
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Continuous spectrometric assay ...
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2002
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The unusually slow relaxation ...
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The X-ray crystal structure of ...
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Kabashima
Enhancement of the thermal sta ...
Bacillus amyloliquefaciens
Biochim. Biophys. Acta
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2001
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Ogasahara
Thermal stability of pyrrolido ...
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2001
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Alur
Inhibition of a model protease ...
Bos taurus
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2001
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Tanaka
X-ray crystalline structures o ...
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2001
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Ito
The mechanism of substrate rec ...
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276
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2001
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653129
Singleton
Pyrrolidone carboxylpeptidase ...
Thermococcus litoralis
Methods Enzymol.
330
394-403
2001
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653412
de Gandarias
Subcellular ontogeny of brain ...
Rattus norvegicus
Peptides
21
509-517
2000
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727453
Singleton
Cloning, expression, and chara ...
Thermococcus litoralis, Thermococcus litoralis DSM 5473
Extremophiles
4
297-303
2000
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95291
Odagaki
The crystal structure of pyrog ...
Bacillus amyloliquefaciens
Structure
7
399-411
1999
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Singleton
Crystallization and preliminar ...
Thermococcus litoralis
Acta Crystallogr. Sect. D
55
702-703
1999
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95316
Singleton
X-ray structure of pyrrolidone ...
Thermococcus litoralis
Structure Fold. Des.
15
237-244
1999
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95297
Ogasahara
The unusually slow unfolding r ...
Bacillus amyloliquefaciens, Pyrococcus furiosus
Biochemistry
37
17537-17544
1998
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95299
Gallagher
A study of a highly specific p ...
Bacillus amyloliquefaciens, Bacillus subtilis, Bos taurus
Int. J. Biochem. Cell Biol.
30
115-133
1998
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2
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1
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Tsunasawa
Pyrrolidone carboxyl peptidase ...
Pyrococcus furiosus
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124
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1998
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Le Saux
Pyroglutamic acid and iron reg ...
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155
209-215
1997
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Le Saux
Mutational analysis of the act ...
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95296
Cummins
Bovine brain pyroglutamyl amin ...
Bos taurus
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28
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1996
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Sanchez
Pyroglutamyl peptidase I level ...
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731
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4
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1
-
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95295
Gonzales
Characterization of the pcp ge ...
Pseudomonas fluorescens
J. Bacteriol.
176
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1994
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1
1
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1
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1
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6
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1
1
1
1
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1
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-
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95300
Awade
Pyrrolidone carboxyl peptidase ...
Bos taurus, Cavia porcellus, Enterobacter cloacae, Enterococcus faecium, Homo sapiens, Oryctolagus cuniculus, Pseudomonas fluorescens, Rattus norvegicus, Streptococcus pyogenes, Sus scrofa
Proteins Struct. Funct. Genet.
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1994
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9
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10
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9
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95294
Awade
One step purification and char ...
Streptococcus pyogenes
FEBS Lett.
308
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1992
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1
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1
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2
1
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1
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1
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95298
Bharadwaj
Pyroglutamate aminopeptidase i ...
Rattus norvegicus
Indian J. Biochem. Biophys.
29
442-444
1992
1
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5
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1
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1
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95303
Gonzales
Purification and characterizat ...
Bacillus subtilis
J. Chromatogr.
584
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1992
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1
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2
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95307
Cleuziat
Molecular characterization of ...
Streptococcus pyogenes
Mol. Microbiol.
6
2051-2063
1992
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95308
Awade
Characterization of the pcp ge ...
Bacillus subtilis
FEBS Lett.
305
67-73
1992
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95309
Ramirez
Bilateral distribution of amin ...
Rattus norvegicus
Exp. Clin. Endocrinol.
99
59-63
1992
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95301
Mantle
Purification and characterizat ...
Homo sapiens
Clin. Chim. Acta
197
35-46
1991
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95310
Ramirez
Diurnal variation and left-rig ...
Rattus norvegicus
Acta Endocrinol.
125
570-573
1991
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95311
Cruz
Neuronal localization of pyrog ...
Mus musculus
J. Neurochem.
56
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1991
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727346
Sokol
Enzyme profiles of Clostridium ...
Clostridioides difficile
Cytobios
66
35-40
1991
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1
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95302
Yamada
Thyrotropin-releasing hormone- ...
Homo sapiens
Proc. Soc. Exp. Biol. Med.
194
346-351
1990
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1
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95312
Charli
Pyroglutamyl peptidase II inhi ...
Rattus norvegicus
Neuropeptides
14
191-196
1989
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95313
Scharfmann
Presence of a particulate thyr ...
Rattus norvegicus
Neuroendocrinology
49
442-448
1989
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95314
Court
Raised thyrotrophin-releasing ...
Mus musculus, Rattus norvegicus
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1987
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95315
Vargas
Regional distribution of the m ...
Rattus norvegicus
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79
311-314
1987
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95277
Capecchi
Substrate specificity of pyrog ...
Bos taurus
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1985
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95278
O'Connor
Purification of and kinetic st ...
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Eur. J. Biochem.
150
47-52
1985
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5
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5
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95279
O'Connor
-
Some properties of synaptosoma ...
Bacillus amyloliquefaciens, Cavia porcellus
Biochem. Soc. Trans.
3
485-487
1985
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1
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95280
Tsuru
-
Pyroglutamate-peptidase from B ...
Bacillus amyloliquefaciens
Biochim. Biophys. Acta
791
117-122
1984
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3
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3
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95281
O'Connor
Localization of a narrow-speci ...
Cavia porcellus
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144
271-278
1984
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95282
Browne
An evaluation of the role of a ...
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Eur. J. Biochem.
137
75-87
1983
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9
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95283
Tsuru
Pyroglutamyl peptidase from ch ...
Gallus gallus
J. Pharmacobio-Dyn.
5
859-868
1982
4
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11
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10
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1
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95284
Fujiwara
Inactivation of pyroglutamyl a ...
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J. Biochem.
90
433-437
1981
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95285
Fujiwara
Inactivation of pyroglutamyl a ...
Bacillus amyloliquefaciens
Biochim. Biophys. Acta
655
10-16
1981
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95286
Fujiwara
N-alpha-Carbobenzoxy-pyrogluta ...
Bacillus amyloliquefaciens
Biochim. Biophys. Acta
702
149-154
1980
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2
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95287
Fujiwara
The substrate specificity of p ...
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Biochim. Biophys. Acta
570
140-148
1979
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16
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23
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95288
Exterkate
-
Reversible inhibition of the m ...
Lactococcus lactis subsp. cremoris
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111-114
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Taylor
Characterization of a pyroglut ...
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-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
1
-
-
1
-
-
-
-
1
-
2
1
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
95290
Tsuru
Purification and characterizat ...
Bacillus amyloliquefaciens, Bacillus circulans, Bacillus megaterium, Bacillus subtilis, Micrococcus luteus, Paenibacillus polymyxa, Pimelobacter simplex, Proteus vulgaris, Pseudomonas aeruginosa
J. Biochem.
84
467-476
1978
-
-
-
-
-
1
10
-
-
5
2
-
-
11
-
-
1
-
-
-
1
2
5
1
-
1
-
1
-
1
1
1
-
-
-
-
-
-
-
-
-
-
1
-
10
-
-
-
5
2
-
-
-
-
1
-
-
1
2
5
1
1
-
1
-
1
1
1
-
-
-
-
-
-
-
95292
Armentrout
Pyrrolidonecarboxylyl peptidas ...
Pseudomonas fluorescens
Arch. Biochem. Biophys.
132
80-90
1969
-
-
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-
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1
1
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-
-
-
-
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1
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1
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-
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1
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2
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
2
-
-
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