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Literature summary for 3.4.19.3 extracted from

  • O'Connor, B.; O'Cuinn, G.
    Localization of a narrow-specificity thyroliberin hydrolyzing pyroglutamate aminopeptidase in synaptosomal membranes of guinea-pig brain (1984), Eur. J. Biochem., 144, 271-278.
    View publication on PubMed
Search for more literature for 3.4.19.3

Inhibitors

Inhibitors Comment Organism Structure
8-hydroxyquinoline
-
 Cavia porcellus
bacitracin weak Cavia porcellus
DTT weak Cavia porcellus
EDTA
-
 Cavia porcellus
iodoacetamide weak Cavia porcellus
NEM weak Cavia porcellus
PCMB weak Cavia porcellus
PMSF
-
 Cavia porcellus
puromycin
-
 Cavia porcellus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane synaptosomal Cavia porcellus 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
230000
-
-
 Cavia porcellus

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acid-thyroliberin + H2O
-
 Cavia porcellus pyroglutamate + His-Pro
-
 ?
pyroglutamyl-His-Gly + H2O
-
 Cavia porcellus pyroglutamate + His-Gly
-
 ?
pyroglutamyl-His-Gly-NH2 + H2O
-
 Cavia porcellus pyroglutamate + His-Gly-NH2
-
 ?
thyroliberin + H2O removes the N-terminal pyroglutamic acid Cavia porcellus pyroglutamate + His-Pro-NH2
-
 ?