Cloned (Comment) | Organism |
---|---|
expressed in KR-4 cells | Mus musculus |
UCH-L1 expression analysis by microarray, quantitative real time-PCR | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | enzyme downregulation by RNAi. UCH L1 suppression inhibits cell proliferation and migration and induces G0/G1 arrest and apoptosis | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
gene uch l1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | increased expression and activity of UCH L1 in EBV-immortalized cell lines | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
ubiquitin C-terminal hydrolase L1 | - |
Mus musculus |
UCH L1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | enzyme downregulation by RNAi in C33A cells. UCH L1 suppression inhibits cell proliferation and migration and induces G0/G1 arrest and apoptosis | down |
Mus musculus | camptothecin induces enzyme expression, also in RNAi silenced 293T and KR4 cells | up |
General Information | Comment | Organism |
---|---|---|
malfunction | UCH L1 is expressed in a number of malignancies, it might be involved in oncogenic processes. UCH L1 suppression induces G0/G1 arrest and apoptosis | Mus musculus |