Application | Comment | Organism |
---|---|---|
analysis | UCH-L1 is a neuronal marker | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | gad, i.e. gracile axonal dystrophy, mice are analogous to a null mutants of UCH-L1, they display the dying-back-type of axonal degeneration in sensory neurons. The level of mono-ubiquitin is decreased in neurons, especially in axons of the sciatic nerve, in gad mice | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25100 | - |
x * 25100, UCH-L1, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | UCH-L1 is a deubiquitinating enzyme, it binds to and stabilize mono-ubiquitin in neurons | ? | - |
? | |
additional information | Mus musculus | UCH-L1 is a deubiquitinating enzyme, it binds to and stabilizes mono-ubiquitin in neurons | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | high expression of UCH-L1 | Mus musculus | - |
ovary | high expression of UCH-L1 | Mus musculus | - |
sciatic nerve | - |
Mus musculus | - |
testis | high expression of UCH-L1 | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | UCH-L1 is a deubiquitinating enzyme, it binds to and stabilize mono-ubiquitin in neurons | Mus musculus | ? | - |
? | |
additional information | UCH-L1 is a deubiquitinating enzyme, it binds to and stabilizes mono-ubiquitin in neurons | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 25100, UCH-L1, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
PGP9.5 | - |
Mus musculus |
ubiquitin carboxyl-terminal hydrolase L1 | - |
Mus musculus |
Ubiquitin thiolesterase | - |
Mus musculus |
UCH-L1 | - |
Mus musculus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Mus musculus | UCH-L1, isoelectric focusing | - |
5.12 |
General Information | Comment | Organism |
---|---|---|
physiological function | UCH-L1 is a deubiquitinating enzyme, it binds to and stabilize mono-ubiquitin in neurons | Mus musculus |
physiological function | UCH-L1 is a deubiquitinating enzyme, it binds to and stabilizes mono-ubiquitin in neurons | Mus musculus |