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Literature summary for 3.4.19.12 extracted from

  • Lu, Y.; Adegoke, O.A.; Nepveu, A.; Nakayama, K.I.; Bedard, N.; Cheng, D.; Peng, J.; Wing, S.S.
    USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1 (2009), Mol. Cell. Biol., 29, 547-558.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.19.12

Cloned(Commentary)

Cloned (Comment) Organism
Flag-USP19 transfected into FR3T3 cells. 293VSV cells transfected with pLXSN plasmid encoding N-terminally Flag3-tagged USP19 Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
C545A catalytically inactive USP19 mutant, destabilizes ubiquitin ligase KPC1 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol USP19 stabilizes the ubiquitin ligase KPC1 and, like KPC1, it is localized in the cytosol Rattus norvegicus 5829
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Organism

Organism UniProt Comment Textmining
Mus musculus Q3UJD6
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Rattus norvegicus Q6J1Y9
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Source Tissue

Source Tissue Comment Organism Textmining
L-6 myoblast cell
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 Rattus norvegicus
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MEF cell
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 Mus musculus
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additional information FR3T3 cell Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
KPC1
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 Rattus norvegicus ?
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 ?

Synonyms

Synonyms Comment Organism
USP19
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 Rattus norvegicus
USP19
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 Mus musculus