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Literature summary for 3.4.19.12 extracted from

  • Ha, M.K.; Soo Cho, J.; Baik, O.R.; Lee, K.H.; Koo, H.S.; Chung, K.Y.
    Caenorhabditis elegans as a screening tool for the endothelial cell-derived putative aging-related proteins detected by proteomic analysis (2006), Proteomics, 6, 3339-3351.
    View publication on PubMed
Search for more literature for 3.4.19.12

Activating Compound

Activating Compound Comment Organism Structure
H2O2
-
 Homo sapiens

Application

Application Comment Organism
additional information UCHL1 is a candidate aging-related protein Homo sapiens
additional information UCHL1 is related to cellular senescence process Caenorhabditis elegans

Inhibitors

Inhibitors Comment Organism Structure
RNAi knockdown of UCHL1, leads to short lifespan of animals and earlier accumulation of aging specific lipofucsin with increasing age when compared with the wild-type Caenorhabditis elegans

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
 variant Bristol
-
Caenorhabditis elegans N2
-
 variant Bristol
-
Homo sapiens P09936
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information HMVEC cells from newborn foreskins Homo sapiens
-

Synonyms

Synonyms Comment Organism
ubiquitin carboxy-terminal hydrolase L1
-
 Caenorhabditis elegans
ubiquitin carboxy-terminal hydrolase L1
-
 Homo sapiens
ubiquitin carboxyl terminal hydrolase L1
-
 Caenorhabditis elegans
ubiquitin carboxyl terminal hydrolase L1
-
 Homo sapiens
UCHL1
-
 Caenorhabditis elegans
UCHL1
-
 Homo sapiens