Cloned (Comment) | Organism |
---|---|
UBPY, DNA sequence determination and analysis, expression of gene fragment, residues 9-188, fused to GST in a bacterial expression system | Homo sapiens |
UBPY, expression of wild-type enzyme and mutant D786A in NIH 3T3 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C786A | site-directed mutagenesis, no activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-ethylmaleimide | UBPY | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
130000 | - |
x * 130000, SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme inhibits cell proliferation | ? | - |
? | |
additional information | Homo sapiens | enzyme regulation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P40818 | UBPY | - |
Purification (Comment) | Organism |
---|---|
recombinant truncated GST-fusion protein of UBPY | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C33A cell | human cervical carcinoma cell line | Homo sapiens | - |
fibroblast | accumulated upon growth stimulation of starved human fibroblasts | Homo sapiens | - |
U2-OS cell | human osteosarcoma cell line | Homo sapiens | - |
WI-38 cell | human fibroblast cell line | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
branched polyubiquitin + H2O | isopeptide-linked ubiquitin chains | Homo sapiens | ubiquitin | - |
? | |
additional information | enzyme inhibits cell proliferation | Homo sapiens | ? | - |
? | |
additional information | enzyme regulation | Homo sapiens | ? | - |
? | |
polyubiquitin + H2O | linear chains | Homo sapiens | ubiquitin | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 130000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
UBPY | - |
Homo sapiens |