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Literature summary for 3.4.18.1 extracted from

  • Zhao, C.F.; Herrington, D.M.
    The function of cathepsins B, D, and X in atherosclerosis (2016), Am. J. Cardiovasc. Dis., 6, 163-170 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UBR2
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General Information

General Information Comment Organism
physiological function cathepsin X plays an important role in the pathogenes of atherosclerosis. It aids in the migration of T-lymphocytes and the release of cytokines. Cathepsin X may aid in the migration of immune cells within the lesion and is predominately implicated in T-lymphocyte signaling and secretion of cytokines that stimulate the proliferation of smooth muscle cells. It may also play a role in localizing inflammatory cells to the shoulder of unstable plaques Homo sapiens