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Literature summary for 3.4.17.23 extracted from
- Altered activities of kininase II, an angiotensin converting enzyme, prekallikrein, and nitric oxide in Kuwaiti patients with type 2 diabetes (2015), Int. J. Immunopathol. Pharmacol., 28, 240-246 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | plasma kininase II or ACE levels are significantly increased by 18% in untreated diabetics when compared with healthy volunteers. After treatment for 6 weeks with metformin hydrochloride 500 mg twice daily there is a significant decrease of 20% in their ACE levels. Plasma prekallikrein levels are raised significantly by 28% in diabetic patients in contrast with the control subjects and the levels are reduced by 44% after treatment with metformin hydrochloride. NO levels are significantly decreased in plasma by 56% and in urine by 62% in untreated diabetic patients as compared with the healthy subjects. In treated diabetic patients' samples, there is an increase of 50% in plasma and 37% in urine samples compared to untreated patients | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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