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Literature summary for 3.4.17.23 extracted from

  • Cao, Y.; Li, L.; Feng, Z.; Wan, S.; Huang, P.; Sun, X.; Wen, F.; Huang, X.; Ning, G.; Wang, W.
    Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations (2020), Cell Discov., 6, 11 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BYF1
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-

Synonyms

Synonyms Comment Organism
ACE2
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 Homo sapiens

General Information

General Information Comment Organism
physiological function the angiotensin-converting enzyme-2 is the receptor for the SARS-coronavirus (SARS-CoV), the human respiratory coronavirus NL63 and Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Comparative genetic analysis of SARS-CoV-2 coronavirus receptor ACE2 in different populations. Systematic analysis of coding-region variants in ACE2 and the expression quantitative trait loci (eQTL) variants, which may affect the expression of ACE2 using the Genotype Tissue Expression database to compare the genomic characteristics of ACE2 among different populations. No direct evidence is identified genetically supporting the existence of coronavirus S-protein binding-resistant ACE2 mutants in different populations Homo sapiens