Application | Comment | Organism |
---|---|---|
medicine | ACE2 may be a target for therapeutic interventions that aim to reduce albuminuria and glomerular injury | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
MLN-4760 | - |
Mus musculus | |
telmisartan | specific angiotensin II type 1 receptor blocker | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
glomerulus | - |
Mus musculus | - |
kidney | ACE and ACE2 co-localized strongly in the apical brush border of the proximal tubule | Mus musculus | - |
podocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin II + H2O | - |
Mus musculus | angiotensin-(1-7) + Phe | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACE2 | - |
Mus musculus |