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Literature summary for 3.4.17.21 extracted from

  • Guo, Z.; Huang, H.; Zeng, L.; Du, T.; Xu, K.; Lin,T.; Jiang, C.; Dong, W.; Cao, Y.; Chen, J.; Zhong, W.; Huang, J.
    Lentivirus-mediated RNAi knockdown of prostate-specific membrane antigen suppresses growth, reduces migration ability and the invasiveness of prostate cancer cells (2011), Med. Oncol., 28, 878-887.
    View publication on PubMed
Search for more literature for 3.4.17.21

Protein Variants

Protein Variants Comment Organism
additional information downregulation of prostate-specific membrane antigen expression by lentivirus-mediated RNA interference significantly suppresses the growth rates of LNCaP and DU-145 cells. The specific down-regulation arrests cells in G0/G1 phase of cell cycle Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane PSMA is a type II membrane protein Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens Q04609
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-
epithelium prostate gland Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-
prostate cancer cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
Prostate-specific membrane antigen
-
 Homo sapiens
PSMA
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens Lentivirus-mediated RNAi inhibits PSMA mRNA and protein expression in LNCaP and DU-145 cells, PSMA RNAi induces the changes of cell cycle, overview down