Literature summary for 3.4.17.21 extracted from

Han, L.; Picker, J.D.; Schaevitz, L.R.; Tsai, G.; Feng, J.; Jiang, Z.; Chu, H.C.; Basu, A.C.; Berger-Sweeney, J.; Coyle, J.T.
Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II (2009), Synapse, 63, 625-635.

Search for more literature for 3.4.17.21

Cloned(Commentary)

Cloned (Comment)	Organism
a 20.7 kb gene fragment encoding exons 1-3 is subcloned and analyzed by restriction mapping	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
2-phosphonomethyl-pentanedoic acid	2-PMPA	Mus musculus
Quisqualic acid	-	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
synaptosome	synaptoneurosome	Mus musculus	-	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	-	Mus musculus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
100000	-	determined by SDS-PAGE and Western Blot analysis	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
N-acetyl-alpha L-aspartyl-L-glutamate + H2O	Mus musculus	-	N-acetyl-L-aspartate + L-glutamate	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
membrane fractions are prepared using mouse brain tissue samples	Mus musculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
astrocyte	-	Mus musculus	-
brain	-	Mus musculus	-
cerebellum	glomeruli in the cerebellum	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-acetyl-alpha L-aspartyl-L-glutamate + H2O	-	Mus musculus	N-acetyl-L-aspartate + L-glutamate	-	?

Synonyms

Synonyms	Comment	Organism
folate hydrolase 1	-	Mus musculus
FOLH1	-	Mus musculus
GCPII	-	Mus musculus
glutamate carboxypeptidase II	-	Mus musculus
N-acetylated-alpha-linked-acidic-dipeptidase	-	Mus musculus
NAALADase	-	Mus musculus
PMSA	-	Mus musculus
prostate specific membrane antigen	-	Mus musculus

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Release 2023.1 (January 2023)