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Literature summary for 3.4.17.21 extracted from

  • Rodriguez, C.E.; Lu, H.; Martinez, A.R.; Hu, Y.; Brunelle, A.; Berkman, C.E.
    Inhibition of glutamate carboxypeptidase II by phosphonamidothionate derivatives of glutamic acid (2001), J. Enzyme Inhib., 16, 359-365.
    View publication on PubMed
Search for more literature for 3.4.17.21

Inhibitors

Inhibitors Comment Organism Structure
(2S)-2-[[butyl(hydroxy)phosphorothioyl]amino]pentanedioic acid
-
 Homo sapiens
(2S)-2-[[ethyl(hydroxy)phosphorothioyl]amino]pentanedioic acid
-
 Homo sapiens
(2S)-2-[[hydroxy(methyl)phosphorothioyl]amino]pentanedioic acid
-
 Homo sapiens
(2S)-2-[[hydroxy(phenyl)phosphorothioyl]amino]pentanedioic acid
-
 Homo sapiens
(2S)-2-[[hydroxy(phenyl)phosphorothioyl]oxy]pentanedioic acid
-
 Homo sapiens
(2S)-2-[[hydroxy(phenyl)phosphoryl]amino]pentanedioic acid
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
PSMA
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000104
-
 (2S)-2-[[butyl(hydroxy)phosphorothioyl]amino]pentanedioic acid pH 7.4, 37°C Homo sapiens
0.000719
-
 (2S)-2-[[hydroxy(methyl)phosphorothioyl]amino]pentanedioic acid pH 7.4, 37°C Homo sapiens
0.00109
-
 (2S)-2-[[ethyl(hydroxy)phosphorothioyl]amino]pentanedioic acid pH 7.4, 37°C Homo sapiens
0.00111
-
 (2S)-2-[[hydroxy(phenyl)phosphoryl]amino]pentanedioic acid pH 7.4, 37°C Homo sapiens
0.00639
-
 (2S)-2-[[hydroxy(phenyl)phosphorothioyl]amino]pentanedioic acid pH 7.4, 37°C Homo sapiens
0.0146
-
 (2S)-2-[[hydroxy(phenyl)phosphorothioyl]oxy]pentanedioic acid pH 7.4, 37°C Homo sapiens