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Literature summary for 3.4.17.20 extracted from

  • Bjoerkman, J.A.; Abrahamsson, T.I.; Nerme, V.K.; Mattsson, C.J.
    Inhibition of carboxypeptidase U (TAFIa) activity improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis (2005), Thromb. Res., 116, 519-524.
    View publication on PubMed
Search for more literature for 3.4.17.20

Inhibitors

Inhibitors Comment Organism Structure
MERGETPA D,L-2-mercaptomethyl-3-guanidinoethyl-thipropanoic acid, a carboxypeptidase inhibitor Canis lupus familiaris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Canis lupus familiaris inhibition of the enzyme leads to facilitated induction of coronary artery thrombolysis involving the plasminogen activator ?
-
 ?

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 hemodynamics in untreated hearts of dogs and hearts treated with enzyme inhibitor MERGETPA and/or plasminogen activator, overview Canis lupus familiaris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information inhibition of the enzyme leads to facilitated induction of coronary artery thrombolysis involving the plasminogen activator Canis lupus familiaris ?
-
 ?

Synonyms

Synonyms Comment Organism
carboxypeptidase U
-
 Canis lupus familiaris
CPU
-
 Canis lupus familiaris
TAFIa
-
 Canis lupus familiaris
thrombin activatable fibrinolysis inhibitor
-
 Canis lupus familiaris