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Literature summary for 3.4.17.15 extracted from
- A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family (1988), J. Biol. Chem., 263, 17828-17836.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.127 | - |
benzyloxycarbonyl-Gly-Trp | - |
Rattus norvegicus |  |
| 0.145 | - |
Benzyloxycarbonyl-Gly-Tyr | - |
Rattus norvegicus | |
| 0.314 | - |
benzyloxycarbonyl-Gly-Gly-Phe | - |
Rattus norvegicus | |
| 6.53 | - |
benzyloxycarbonyl-Gly-Gly-Leu | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-Gly-Gly-Leu + H2O | - |
Rattus norvegicus | ? | - |
? | |
| benzyloxycarbonyl-Gly-Gly-Phe + H2O | - |
Rattus norvegicus | ? | - |
? | |
| benzyloxycarbonyl-Gly-Gly-Trp + H2O | - |
Rattus norvegicus | ? | - |
? | |
| benzyloxycarbonyl-Gly-Phe + H2O | - |
Rattus norvegicus | ? | - |
? | |
| benzyloxycarbonyl-Gly-Trp + H2O | - |
Rattus norvegicus | ? | - |
? | |
| benzyloxycarbonyl-Gly-Tyr + H2O | - |
Rattus norvegicus | ? | - |
? | |
| additional information | carboxy-terminal amino acids with aromatic or branched aliphatic side chains are preferred | Rattus norvegicus | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 14 | - |
benzyloxycarbonyl-Gly-Gly-Leu | - |
Rattus norvegicus | |
| 14.4 | - |
Benzyloxycarbonyl-Gly-Tyr | - |
Rattus norvegicus | |
| 16.8 | - |
Benzyloxycarbonyl-Gly-Phe | - |
Rattus norvegicus | |
| 26.6 | - |
benzyloxycarbonyl-Gly-Trp | - |
Rattus norvegicus | |
| 96.9 | - |
benzyloxycarbonyl-Gly-Gly-Trp | - |
Rattus norvegicus | |
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