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Literature summary for 3.4.17.12 extracted from

  • De Beuf, A.; Hou, X.H.; DHaese, P.C.; Verhulst, A.
    Epoetin delta reduces oxidative stress in primary human renal tubular cells (2010), J. Biomed. Biotechnol., 2010, 395785.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
additional information primary human renal tubular epithelial cell Homo sapiens
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Synonyms

Synonyms Comment Organism
carboxypeptidase M
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 Homo sapiens
CPM
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens oxidative stress reduction by epoetin delta goes along with the upregulation of renoprotective genes. The expression of carboxypeptidase M is significantly upregulated upon erythropoietin administration in and only in those cell cultures in which an erythropoietin-induced cytoprotective effect is seen. In cultures in which epoetin delta does not show protective effects, no upregulation of carboxypeptidase M is observed up