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Literature summary for 3.4.17.12 extracted from

  • Marquez-Curtis, L.; Jalili, A.; Deiteren, K.; Shirvaikar, N.; Lambeir, A.M.; Janowska-Wieczorek, A.
    Carboxypeptidase M expressed by human bone marrow cells cleaves the C-terminal lysine of SDF-1{alpha}: Another player in hematopoietic stem/progenitor cell mobilization? (2008), Stem Cells, 26, 1211-1220.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
G-CSF granulocyte-colony stimulating factor Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
DL-2-mercaptomethyl-3-guanidino-ethylthiopropanoic acid
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone marrow
-
Homo sapiens
-
erythroid cell erythroid cell progenitor Homo sapiens
-
hematopoietic cell
-
Homo sapiens
-
marrow cell myeloid cell progenitor Homo sapiens
-
megakaryocyte megakaryocytic cell progenitor Homo sapiens
-
mesenchymal stem cell
-
Homo sapiens
-
mononuclear cell
-
Homo sapiens
-
peripheral blood cell mobilized peripheral blood CD34+ cell Homo sapiens
-
polymorphonuclear cell
-
Homo sapiens
-
stromal cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
SDF-1alpha + H2O stromal cell-derived factor Homo sapiens des-lys SDF-1alpha + lysine
-
?

Synonyms

Synonyms Comment Organism
carboxypeptidase M
-
Homo sapiens
CPM
-
Homo sapiens