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Literature summary for 3.4.17.12 extracted from

  • Tsakiris, I.; Soos, G.; Nemes, Z.; Kiss, S.S.; Andras, C.; Szanto, J.; Dezso, B.
    The presence of carboxypeptidase-M in tumour cells signifies epidermal growth factor receptor expression in lung adenocarcinomas: The coexistence predicts a poor prognosis regardless of EGFR levels (2008), J. Cancer Res. Clin. Oncol., 134, 439-451.
    View publication on PubMed
Search for more literature for 3.4.17.12

Application

Application Comment Organism
medicine the present data could lead to improved IHC tests in lung adenocarcinomas when the prognostic value of EGFR expression needs to be evaluated for a target therapy especially when EGFR gene exhibited to mutations Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
EGF + H2O Homo sapiens EGF, epidermal growth factor des-Arg53-EGF + arginine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung adenocarcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
EGF + H2O EGF, epidermal growth factor Homo sapiens des-Arg53-EGF + arginine
-
 ?

Synonyms

Synonyms Comment Organism
carboxypeptidase M
-
 Homo sapiens
CPM
-
 Homo sapiens